Monday, July 4, 2022

WHO Releases 10-Year Strategy For Genomic Surveillance Of Pathogens

World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus gives a press conference on the situation regarding the COVID-19 at Geneva's WHO headquarters on February 24, 2020. - Fears of a global coronavirus pandemic deepened on February 24 as new deaths and infections in Europe, the Middle East and Asia triggered more drastic efforts to stop people travelling. (Photo by Fabrice COFFRINI / AFP) (Photo by FABRICE COFFRINI/AFP via Getty Images)
The director-general, World Health Organization, Dr. Tedros Ghebreyesus.

The World Health Organization (WHO) said it has released a strategy to strengthen and scale up genomic surveillance around the world.

Historically, few countries have routinely done genomic surveillance in-country, a technology considered complicated and expensive. But COVID-19 changed that.

Genomic surveillance is the process of constantly monitoring pathogens and analysing their genetic similarities and differences. It helps researchers, epidemiologists and public health officials to monitor the evolution of infectious diseases agents, alert on the spread of pathogens, and develop counter-measures like vaccines.

The Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022–2032 is not specific to a single pathogen or disease threat. It provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance worldwide.

Data collected by the WHO shows that in March 2021, 54 per cent of countries had this capacity. By January 2022, thanks to the major investments made during the COVID-19 pandemic, the number had increased to 68 per cent. Even greater gains were made in the public sharing of sequence data: in January 2022, 43 per cent more countries published their sequence data compared to 2021.

Despite this fast progress, much remains to be done. Any new technology comes with the risk of increasing inequity, which is one of the gaps this strategy targets.

Various public health programmes – from Ebola to cholera – use genomic surveillance to understand a pathogen at its molecular level, but COVID-19 has highlighted the challenges of bringing genomics to scale.

“The complexities of genomics and the challenges of sustaining capacities in different settings, including workforce needs, mean that most countries cannot develop these capabilities on their own. The global strategy helps keep our eyes on the horizon and provides a unifying framework for action. WHO looks forward to working with countries and partners in this important and highly dynamic field,” said WHO director-general, Dr. Tedros Ghebreyesus. “We will do best if we work together.”

The COVID-19 pandemic has shown that health systems need genomic surveillance so that risks are rapidly detected and addressed. This technology has been critical in this response, from the identification of a novel coronavirus to the development of the first diagnostic tests and vaccines to the tracking and identification of new virus variants. 

“Genomic surveillance is critical for stronger pandemic and epidemic preparedness and response,” said executive director, WHO health emergencies programme, Dr. Michael Ryan. “This pandemic has laid bare the fact that we live in an interconnected world and that we are only as strong as our weakest link. Improving global disease surveillance means improving local disease surveillance. That is where we need to act, and this strategy will provide us with the foundation.”

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